A stochastic inventory model of COVID-19 and robust, real-time identification of carriers at large and infection rate via asymptotic lawsResearch article Published on 2023-01-012022-10-05 Journal: European Journal of Operational Research [Category] 변종, [키워드] affecting Asymptomatic asymptotic Care carrier COVID-19 COVID-19 incidence COVID-19 pandemic Critical data-driven deaths distribution Epidemic modeling Evolution fraction Health incidence infection rate Little's law management manifested Measures National Operations management under uncertainty OR in health services Outbreaks Patient Perspective profiles provide random Randomly reconstructed robust scaled Spread symptomatic carrier the disease the mean the SARS-CoV-2 trajectory variable variables [DOI] 10.1016/j.ejor.2021.12.037 [Article Type] Research article
SARS-CoV-2 infection dynamics revealed by wastewater sequencing analysis and deconvolutionArticle Published on 2022-12-202022-11-15 Journal: The Science of the total environment [Category] COVID19(2023년), SARS, 변종, 치료기술, 치료제, [키워드] Accuracy analyses Analysis approach automated B.1.617.2 Berlin can be used changes in circulating computational analysis concern continuous monitoring COVID-19 COVID-19 surveillance Critical dataset detect develop effort environmental monitoring Health highlight identify in silico in-depth analysis include independent individual Infection infection rate Lineage MONITOR Mutation New York City pathogen proportion provide Public Public health risk raw data RBD RNA sequencing SARS-CoV-2 SARS-COV-2 infection sequenced Sequencing Sequencing analysis sequencing data sewage Sewage sampling. shown Support virus viruses VoC while [DOI] 10.1016/j.scitotenv.2022.158931 PMC 바로가기
Reverse transcriptase-free detection of viral RNA using Hemo Klentaq DNA polymeraseArticle Published on 2022-12-152022-11-15 Journal: Analytical biochemistry [Category] COVID19(2023년), SARS, 치료기술, 치료제, [키워드] affected amplification Analysis can be used caused comparable COVID-19 Degraded RNA demonstrated determine DNA polymerase Efficiency freeze-thaw cycles limitations Nasopharyngeal swab Nearby Nearby primers overcome pandemic patients PCR polymerase chain polymerase chain reaction Primers provide provided reliability reverse transcriptase Reverse transcriptase activity reverse transcription RNA RT-PCR SARS-CoV-2 SARS-CoV-2 detection target transcriptase Viral RNA Viral RNA. [DOI] 10.1016/j.ab.2022.114960 PMC 바로가기
Ultraminiature optical fiber-tip directly-printed plasmonic biosensors for label-free biodetectionArticle Published on 2022-12-152022-11-15 Journal: Biosensors & bioelectronics [Category] COVID19(2023년), SARS, 치료기술, [키워드] Additive Additive printing antibody AuNP Biomarker Concentration coronavirus disease detect Diagnosis diagnostics disease Diseases DNA sequence fiber gold Gold nanoparticle Gold nanoparticles imperative in vivo miniaturization offer optical Optical fiber optical fiber sensors pandemic Plasmonic biosensor point-of-care Precision Precision photoreduction. provide public health crisis SARS-CoV-2 [DOI] 10.1016/j.bios.2022.114761 PMC 바로가기
Combining intramuscular and intranasal homologous prime-boost with a chimpanzee adenovirus-based COVID-19 vaccine elicits potent humoral and cellular immune responses in mice근육내 및 비강내 상동 프라임-부스트를 침팬지 아데노바이러스 기반 COVID-19 백신과 결합하면 마우스에서 강력한 체액성 및 세포성 면역 반응을 이끌어냅니다.Article Published on 2022-12-012022-09-11 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] acute respiratory syndrome acute respiratory syndrome coronavirus acute respiratory syndrome coronavirus 2 addition Adenovirus adenovirus-based Adenovirus-vectored vaccine Administered antibody titres approach BALB/c mice booster Cellular immune response ChAdTS-S coronavirus coronavirus disease Coronavirus disease 2019 COVID-19 COVID-19 pandemic COVID-19 vaccine COVID-19 vaccines cytokine decrease Efficacy elicit elicited evaluated followed by group highest homologous humoral IFN-γ IFN-γ ELISPOT IgA IgG immune immune responses immunogenicity intracellular cytokine staining intramuscular intramuscular vaccination intranasal intranasal. Meso Scale Discovery mice prime immunization priming protocol provide pseudovirus neutralizing antibody respiratory responsible SARS-CoV-2 serotype shown T-cell Response T-cell responses tested titre vaccination Vaccine variants vectored vaccine [DOI] 10.1080/22221751.2022.2097479 PMC 바로가기 [Article Type] Article
Differential transcriptomic landscapes of multiple organs from SARS-CoV-2 early infected rhesus macaquesSARS-CoV-2 초기 감염된 붉은털 원숭이의 여러 기관의 차등 전사체 풍경Article Published on 2022-12-012022-09-11 Journal: Protein & Cell [Category] COVID19(2023년), SARS, 유전자 메커니즘, 진단, [키워드] accompanied analyzed Angiogenesis cause Central nervous system cerebral cortex changes in clinical complications clinical manifestation clinical manifestations CNS Coagulation controls drastic dysregulation early infection elevated Encephalitis evidenced examined exhibited expression expressions Factor fibrosis function Genes hyperinflammatory state immune response immune responses infected with SARS-CoV-2 Infection Inflammation inflammation response Inflammatory factor inflammatory factors mechanism multiple organ neuropilin 1 NRP1 organs positive positive feedback post infection provide receptor rhesus rhesus macaque right ventricle SARS-CoV-2 SARS-COV-2 infection significantly tissue tissues transcriptomic transcriptomic alteration Transmission up-regulated upregulation Viral viral encephalitis viral encephalitis. [DOI] 10.1007/s13238-022-00915-5 PMC 바로가기 [Article Type] Article
Structure-based neutralizing mechanisms for SARS-CoV-2 antibodiesArticle Published on 2022-12-012022-11-15 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 진단, [키워드] antibody Antibody structure caused consequence COVID-19 pandemic Critical cryo-EM develop effective effort epitope Host Infection mAbs mechanism molecular monoclonal antibody Neutralizing neutralizing antibody neutralizing mechanism pan-coronavirus vaccine. provide public health SARS-CoV-2 SARS-CoV-2 antibody Scientific community the spike protein Vaccine Vaccines [DOI] 10.1080/22221751.2022.2125348 PMC 바로가기
A 1-year longitudinal study on COVID-19 convalescents reveals persistence of anti-SARS-CoV-2 humoral and cellular immunityCOVID-19 회복기에 대한 1년 종단 연구는 항 SARS-CoV-2 체액성 및 세포성 면역의 지속성을 보여줍니다Article Published on 2022-12-012022-09-11 Journal: Emerging Microbes & Infections [Category] COVID19(2023년), SARS, 변종, 진단, [키워드] 1-year after infection anti-SARS-CoV-2 humoral antibody antibody durability. caused CD4 CD8 CD8 T cell CD8 T cell responses Cell cellular immunity central memory circulating antibodies circulating antibody Cohort convalescent COVID-19 COVID-19 convalescent COVID-19 patient disease disease severity effective IgG level immune Immune components immune memory immune protection Immunity induce Infection information Kinetics maintain memory memory B memory B cell Memory responses memory T cells omicron Omicron variant peptide peptide pool persistence protective immunity provide RBD IgG Re-infection recorded response reveal SARS-CoV-2 SARS-CoV-2 circulating antibodies SARS-COV-2 infection subject Symptom T cell T cell response T cell responses T cells tested the RBD the SARS-CoV-2 variant [DOI] 10.1080/22221751.2022.2049984 PMC 바로가기 [Article Type] Article
Photocatalytic degradation of COVID-19 related drug arbidol hydrochloride by Ti3C2 MXene/supramolecular g-C3N4 Schottky junction photocatalystArticle Published on 2022-12-012022-11-15 Journal: Chemosphere [Category] 치료제, [키워드] Affect antiviral drug Arbidol arbidol hydrochloride composed COVID-19 COVID-19 outbreak Degradation drug increasingly less mechanism pathway Photocatalytic degradatiion provide Result resulting Schottky junction SEM significantly superoxide radical Supramolecular g-C(3)N(4) TEM Ti(3)C(2). Toxicity Treatment [DOI] 10.1016/j.chemosphere.2022.136461 PMC 바로가기
Current trends in COVID-19 diagnosis and its new variants in physiological fluids: Surface antigens, antibodies, nucleic acids, and RNA sequencingReview article Published on 2022-12-012022-10-05 Journal: TrAC Trends in Analytical Chemistry [Category] 바이오마커, 변종, 진단, 치료기술, [키워드] addressed antibodies antibody Antigen antigens Beta Biomarker biosensors Blood body fluid circulation clustered regularly interspaced short palindromic repeats COVID-19 COVID-19 diagnosis COVID-19 virus diagnosis CRISPR Critical current Delta Detection sensitivity diagnostic early stage ELISA enzyme-linked immunosorbent enzyme-linked immunosorbent assay Gamma Infection isothermal amplification lateral flow immunoassay LFIA limit Loop-mediated isothermal amplification microarray analysis Microarray assays Mutation nucleic acid nucleic acids omicron outbreak overcome palindromic repeat physiological provide Rapid reduce reverse transcriptase-polymerase chain reaction reverse transcription RNA sequencing RT-LAMP RT-PCR Saliva SARS-CoV-2 Semen specificity Spread surface Urine variant variants virus viruses [DOI] 10.1016/j.trac.2022.116750 [Article Type] Review article